First Proximity Network Kit and Software for protein interactome analysis of single cells at high capacity
The first product to analyze the spatial location of cell surface protein markers providing protein clustering, colocalization and abundance data at an unprecedented throughput.
OUR PRODUCTS
Analyzing the protein interactome at high multiplex and discovering complex and functional cell surface protein rearrangements
Finding new biomarkers based on protein clustering for patient stratification
Enhancing the understanding of therapy mode-of-action
Assessing cell-to-cell interaction levels in suspensions of cells
Providing novel insights on the molecular basis of cellular behavior
The Pixelgen Proxiome Kit, Immuno 155 offers a unique ability to map the protein interactome of single cells. The dynamic interactome is an understudied dimension in translational research with massive potential for discovering novel biomarkers, drug targets, drug mode-of-action understanding, cell-to-cell interactions, and discovery of new therapeutic avenues.
Product Features
Application: cell surface protein interactomics studies
Resolution: nanoscale (approximately ~50 nm)
Multiplex: 155 cell surface protein markers in parallel (all against all)
Cell input: about 100 000 – 500 000 cells
Data output: protein clustering, colocalization and abundance
Supported sample input: fixed cells in suspension originating from PBMCs, BM, dissociated organoids, or fresh frozen tissue
Species: human
Instrument: no instrument and easy NGS sample preparation protocol
Analysis: open source analysis pipelines for data processing and analysis
8 reactions per kit, 1000 cells data output per reaction
Research areas: hematology, CAR-T / cell therapy, immuno oncology and immunology
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